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Article

Mutation scanning of BRAF, NRAS, KIT, and GNAQ/GNA11 in oral mucosal melanoma: a study of 57 cases.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Apr 2016

Lyu Jiong, Wu Yunteng, Li Chaojun, Wang Runxiang, Song Hao, Ren Guoxin, Guo Wei

Abstract excerpt

BACKGROUND: Recent advances in novel targeted therapies have created the need for molecular characterization of cancer to allow accurate personalized treatments. In this study, our aim was to investigate the incidence of activating mutations of oncogenes BRAF, NRAS, KIT, and GNAQ/GNA11 in oral mucosal melanoma. METHODS: We analyzed a cohort of 57 oral mucosal melanoma samples, including 27 frozen samples and 30...

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Identifiers

PMID: 26399561
DOI: 10.1111/jop.12358

Genes

BRAF
KIT
GNA11
GNAQ
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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