Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KIT, NRAS and BRAF mutations in sinonasal mucosal melanoma: a study of 56 cases.

British journal of cancer - 6 Aug 2013

Zebary A, Jangard M, Omholt K, Ragnarsson-Olding B, Hansson J

Abstract excerpt

BACKGROUND: Mucosal melanomas in the head and neck region are most frequently located in the nasal cavity and paranasal sinuses. Sinonasal mucosal melanoma (SNMM) comprises <1% of all melanomas. The aim was to determine the KIT, NRAS and BRAF mutation frequencies in a large series of primary SNMMs. METHODS: Laser capture microdissection was used to isolate tumour cells from 56 formalin-fixed paraffin-embedded...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to GTP Phosphohydrolases
Share to Laser Capture Microdissection
Share to Melanoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Paraffin Embedding

Share to Paranasal Sinus Neoplasms

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins c-kit

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 23860532
DOI: 10.1038/bjc.2013.373
PMCID: PMC3738146

Genes

NRAS
BRAF
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KIT, NRAS and BRAF mutations in sinonasal mucosal melanoma: a study of 56 cases.PMID 23860532Read ↗

Mutation status among patients with sinonasal mucosal melanoma and its impact on survivalSemantic proximity Read ↗

BRAF, NRAS, KIT, TERT, GNAQ/GNA11 mutation profile analysis of head and neck mucosal melanomas: a study of 42 cases.Semantic proximity Read ↗

Alterations in key signaling pathways in sinonasal tract melanoma. A molecular genetics and immunohistochemical study of 90 cases and comprehensive review of the literature.Semantic proximity Read ↗

Sinonasal mucosal melanoma: Molecular profile and therapeutic implications from a series of 32 cases.Semantic proximity Read ↗

Gene mutations and clinical prognosis of mucosal melanoma in different locations of head and neck.Semantic proximity Read ↗

Oncogene abnormalities in a series of primary melanomas of the sinonasal tract: NRAS mutations and cyclin D1 amplification are more frequent than KIT or BRAF mutations.Semantic proximity Read ↗

SF3B1, NRAS, KIT, and BRAF Mutation; CD117 and cMYC Expression; and Tumoral Pigmentation in Sinonasal MelanomasSemantic proximity Read ↗

Mutation scanning of BRAF, NRAS, KIT, and GNAQ/GNA11 in oral mucosal melanoma: a study of 57 cases.Semantic proximity Read ↗

Targeted next-generation sequencing of Japanese patients with sinonasal mucosal melanomas identifies frequent NRAS and CTNNB1 mutations.Semantic proximity Read ↗

Gene Mutation Characteristics and Clinical Prognosis of Head and Neck Mucosal MelanomaSemantic proximity Read ↗

Frequency of mutations in BRAF, NRAS, and KIT in different populations and histological subtypes of melanoma: a systemic reviewSemantic proximity Read ↗

TERT promoter mutations in sinonasal malignant melanoma: a study of 49 cases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.