Article
Single palindromic molecular beacon-based amplification for genetic analysis of cancers.
Biosensors & bioelectronics - 15 May 2017
Li Feng, Zhao Hui, Wang Zheng-Yong, Wu Zai-Sheng, Yang Zhe, Li Cong-Cong, Xu Huo, Lyu Jian-Xin, Shen Zhi-Fa
Abstract excerpt
The detection of biomarkers is of crucial importance in reducing the morbidity and mortality of complex diseases. Thus, there is a great desire to develop highly efficient and simple sensing methods to fulfill the different diagnostic and therapeutic purposes. Herein, using tumor suppressor p53 gene as model target DNA, we developed a novel palindromic fragment-incorporated molecular beacon (P-MB) that can...
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