Article
Modulation of temporal dynamics of gene transcription by activator potency in the Drosophila embryo.
Development (Cambridge, England) - 1 Nov 2015
Liu Junbo, Ma Jun
Abstract excerpt
The Drosophila embryo at the mid-blastula transition (MBT) concurrently experiences a receding first wave of zygotic transcription and the surge of a massive second wave. It is not well understood how genes in the first wave become turned off transcriptionally and how their precise timing may impact embryonic development. Here we perturb the timing of the shutdown of Bicoid (Bcd)-dependent hunchback (hb)...
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