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Article

Interplay between positive and negative activities that influence the role of Bicoid in transcription.

Nucleic acids research - 1 Jan 2005

Fu Dechen, Ma Jun

Abstract excerpt

The Drosophila mophogenetic protein Bicoid (Bcd) can activate transcription in a concentration-dependent manner in embryos. It contains a self-inhibitory domain that can interact with the co-repressor Sin3A. In this report, we study a Bcd mutant, Bcd(A57-61), which has a strengthened self-inhibitory function and is unable to activate the hb-CAT reporter in Drosophila cells, to analyze the role of co-factors in...

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Share to Acetyltransferases
Share to CREB-Binding Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

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Source

Open in PubMed Open full text

Identifiers

PMID: 16030350
DOI: 10.1093/nar/gki691
PMCID: PMC1178001

Genes

CAT
TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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