Article
Autonomous concentration-dependent activation and repression of Krüppel by hunchback in the Drosophila embryo.
Development (Cambridge, England) - 1 Oct 1994
Schulz C, Tautz D
Abstract excerpt
The subdivision of the anterior-posterior axis in Drosophila is achieved by a cascade of spatially regulated transcription factors which form short-range gradients at the syncytial blastoderm stage. These factors are assumed to have concentration-dependent regulatory effects on their target genes. However, there is so far little direct in vivo evidence that a single factor can autonomously activate and repress a...
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