Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shaping a morphogen gradient for positional precision.

Biophysical journal - 4 Aug 2010

He Feng, Saunders Timothy E, Wen Ying, Cheung David, Jiao Renjie, ten Wolde Pieter Rein, Howard Martin, Ma Jun

Abstract excerpt

Morphogen gradients, which provide positional information to cells in a developing tissue, could in principle adopt any nonuniform profile. To our knowledge, how the profile of a morphogen gradient affects positional precision has not been well studied experimentally. Here, we compare the positional precision provided by the Drosophila morphogenetic protein Bicoid (Bcd) in wild-type (wt) embryos with embryos...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Drosophila melanogaster
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to Homeodomain Proteins

Share to p300-CBP Transcription Factors

Share to Trans-Activators

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 20682246
DOI: 10.1016/j.bpj.2010.04.073
PMCID: PMC2913175

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shaping a morphogen gradient for positional precision.PMID 20682246Read ↗

Dampened regulates the activating potency of Bicoid and the embryonic patterning outcome in Drosophila.Semantic proximity Read ↗

Establishment of developmental precision and proportions in the early Drosophila embryo.Semantic proximity Read ↗

The dynamic transmission of positional information in stau- mutants during Drosophila embryogenesis.Semantic proximity Read ↗

Gene expression noise in spatial patterning: hunchback promoter structure affects noise amplitude and distribution in Drosophila segmentation.Semantic proximity Read ↗

Spatial bistability generates hunchback expression sharpness in the Drosophila embryo.Semantic proximity Read ↗

Modulation of temporal dynamics of gene transcription by activator potency in the Drosophila embryo.Semantic proximity Read ↗

Embryonic geometry underlies phenotypic variation in decanalized conditions.Semantic proximity Read ↗

Finding the center reliably: robust patterns of developmental gene expression.Semantic proximity Read ↗

Whole-embryo modeling of early segmentation in Drosophila identifies robust and fragile expression domains.Semantic proximity Read ↗

Manipulating the sensitivity of signal-induced repression: quantification and consequences of altered brinker gradients.Semantic proximity Read ↗

The pattern of nodal morphogen signaling is shaped by co-receptor expression.Semantic proximity Read ↗

Autonomous concentration-dependent activation and repression of Krüppel by hunchback in the Drosophila embryo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.