Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from Monkeys

22 Sept 2015

Abstract excerpt

Cross-species transmissions of viruses from animals to humans are at the origin of major human pathogenic viruses. While the role of ecological and epidemiological factors in the emergence of new pathogens is well documented, the importance of host factors is often unknown. Chimpanzees are the closest relatives of humans and the animal reservoir at the origin of the human AIDS pandemic. However, despite being...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26394054
DOI: 10.1371/journal.ppat.1005149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of the Antiviral APOBEC3 Gene Family in Protecting Chimpanzees against Lentiviruses from MonkeysPMID 26394054Read ↗

Examination of the APOBEC3 Barrier to Cross Species Transmission of Primate LentivirusesSemantic proximity Read ↗

Convergence and divergence in the evolution of the APOBEC3G-Vif interaction reveal ancient origins of simian immunodeficiency viruses.Semantic proximity Read ↗

The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict.Semantic proximity Read ↗

Gorilla APOBEC3 restricts SIVcpz and influences lentiviral evolution in great ape cross-species transmissionsSemantic proximity Read ↗

APOBEC3G Polymorphism as a Selective Barrier to Cross-Species Transmission and Emergence of Pathogenic SIV and AIDS in a Primate HostSemantic proximity Read ↗

Stably expressed APOBEC3H forms a barrier for cross-species transmission of simian immunodeficiency virus of chimpanzee to humansSemantic proximity Read ↗

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1Semantic proximity Read ↗

The Battle between Retroviruses and APOBEC3 Genes: Its Past and Present.Semantic proximity Read ↗

Replicative fitness and pathogenicity of primate lentiviruses in lymphoid tissue, primary human and chimpanzee cells: relation to possible jumps to humansSemantic proximity Read ↗

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G.Semantic proximity Read ↗

APOBEC3F Constitutes a Barrier to Successful Cross-Species Transmission of Simian Immunodeficiency Virus SIVsmm to Humans.Semantic proximity Read ↗

Molecular Ecology and Natural History of Simian Foamy Virus Infection in Wild-Living ChimpanzeesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.