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Examination of the APOBEC3 Barrier to Cross Species Transmission of Primate Lentiviruses

7 Jun 2021

Abstract excerpt

The transmission of viruses from animal hosts into humans have led to the emergence of several diseases. Usually these cross-species transmissions are blocked by host restriction factors, which are proteins that can block virus replication at a specific step. In the natural virus host, the restriction factor activity is usually suppressed by a viral antagonist protein, but this is not the case for restriction...

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PMID: 34200141
DOI: 10.3390/v13061084

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