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Article

Tricornered Kinase Regulates Synapse Development by Regulating the Levels of Wiskott-Aldrich Syndrome Protein.

PloS one - 1 Jan 2015

Natarajan Rajalaxmi, Barber Kara, Buckley Amanda, Cho Phillip, Egbejimi Anuoluwapo, Wairkar Yogesh P

Abstract excerpt

Precise regulation of synapses during development is essential to ensure accurate neural connectivity and function of nervous system. Many signaling pathways, including the mTOR (mechanical Target of Rapamycin) pathway operate in neurons to maintain genetically determined number of synapses during development. mTOR, a kinase, is shared between two functionally distinct multi-protein complexes- mTORC1 and mTORC2,...

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Source

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Identifiers

PMID: 26393506
DOI: 10.1371/journal.pone.0138188
PMCID: PMC4578898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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