Article
The target of rapamycin complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway.
The EMBO journal - 16 Dec 2009
Koike-Kumagai Makiko, Yasunaga Kei-ichiro, Morikawa Rei, Kanamori Takahiro, Emoto Kazuo
Abstract excerpt
To cover the receptive field completely and non-redundantly, neurons of certain functional groups arrange tiling of their dendrites. In Drosophila class IV dendrite arborization (da) neurons, the NDR family kinase Tricornered (Trc) is required for homotypic repulsion of dendrites that facilitates dendritic tiling. We here report that Sin1, Rictor, and target of rapamycin (TOR), components of the TOR complex 2...
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