Article
Drosophila RSK negatively regulates bouton number at the neuromuscular junction.
Developmental neurobiology - 1 Mar 2009
Fischer Matthias, Raabe Thomas, Heisenberg Martin, Sendtner Michael
Abstract excerpt
Ribosomal S6 kinases (RSKs) are growth factor-regulated serine-threonine kinases participating in the RAS-ERK signaling pathway. RSKs have been implicated in memory formation in mammals and flies. To characterize the function of RSK at the synapse level, we investigated the effect of mutations in the rsk gene on the neuromuscular junction (NMJ) in Drosophila larvae. Immunostaining revealed transgenic expressed...
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