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Article

Unpeaceful roles of mutant PAX proteins in cancer.

Seminars in cell & developmental biology - 1 Aug 2015

Wachtel Marco, Schäfer Beat W

Abstract excerpt

PAX transcription factors are key players in the development of different tissues and organs. At the cellular level they are involved in regulating lineage commitment and differentiation. Interference with these tightly regulated functions of PAX proteins is associated with developmental abnormalities and tumorigenesis of several types of cancer. As a result of aberrant PAX protein activity, either by gain- or...

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Identifiers

PMID: 26391565
DOI: 10.1016/j.semcdb.2015.09.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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