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Article

[IGHV mutational statue in patients with splenic marginal zone lymphoma].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Sept 2016

Yang W J, Yu Z, Lyu R, Li Z J, Li H, Xiong W J, Yi S H, Liu W, Qiu L G

Abstract excerpt

Objective: To investigate the IGHV mutational status and its differences from Caucasian in splenic marginal zone lymphoma (SMZL). Methods: A retrospective study on 40 SMZL cases were performed to detect the V-D-J sequence of IGHV by plasmid cloning sequencing, comparing the data with the most homologous germ line V sequence in database, identifying the stereotype of patients through cluster analysis and...

Topics

Chromosome Aberrations
Humans
Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma, B-Cell, Marginal Zone
Mutation
Proteins
Retrospective Studies
Splenic Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 27719720
DOI: 10.3760/cma.j.issn.0253-2727.2016.09.009
PMCID: PMC7342109

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