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Article

Alterations of Nuclear Architecture and Epigenetic Signatures during African Swine Fever Virus Infection

15 Sept 2015

Abstract excerpt

Viral interactions with host nucleus have been thoroughly studied, clarifying molecular mechanisms and providing new antiviral targets. Considering that African swine fever virus (ASFV) intranuclear phase of infection is poorly understood, viral interplay with subnuclear domains and chromatin architecture were addressed. Nuclear speckles, Cajal bodies, and promyelocytic leukaemia nuclear bodies (PML-NBs) were...

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PMID: 26389938
DOI: 10.3390/v7092858

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