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Revisiting the early event of African swine fever virus DNA replication

30 May 2025

Abstract excerpt

ABSTRACT As a member of nucleocytoplasmic large DNA viruses, African swine fever virus (ASFV) has been proposed to include an intriguing nuclear stage for DNA replication. In this report, we revisited this early event by using the ASFV type II strain HN09 as a model organism. Our studies began with dissecting the early stages of the ASFV life cycle via analyses by viral growth kinetics, electron microscopy, and...

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PMID: 40444991
DOI: 10.1128/jvi.00584-25

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