Article

Nonstructural protein 1 of swine arterivirus PRRSV downregulates promyelocytic leukemia nuclear bodies and promotes viral replication

2023-08-04

Abstract excerpt

<h4>ABSTRACT</h4> Porcine reproductive and respiratory syndrome virus (PRRSV) inhibits the type I interferon (IFN) production and signaling pathways during infection, and the nonstructural protein 1 (nsp1) has been identified as a potent IFN antagonist. Promyelocytic leukemia (PML) protein is a major scaffold protein organizing the PML nuclear bodies (NBs) of the cell and plays a diverse role in maintaining the c...

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Literature Corpus work: cfcd6695-b52c-547a-a7e3-a4b661b0ee0a
DOI: 10.1101/2023.08.04.552021

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