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Transcription regulation of African swine fever virus: dual role of M1249L

20 Nov 2024

Abstract excerpt

African swine fever virus (ASFV), which poses significant risks to the global economy, encodes a unique host-independent transcription system. This system comprises an eight-subunit RNA polymerase (vRNAP), temporally expressed transcription factors and transcript associated proteins, facilitating cross-species transmission via intermediate host. The protein composition of the virion and the presence of...

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PMID: 39567541
DOI: 10.1038/s41467-024-54461-1

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