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Speckles and paraspeckles coordinate to regulate HSV-1 genes transcription

21 Oct 2021

Abstract excerpt

Numbers of nuclear speckles and paraspeckles components have been demonstrated to regulate herpes simplex virus 1 (HSV-1) replication. However, how HSV-1 infection affects the two nuclear bodies, and whether this influence facilitates the expression of viral genes, remains elusive. In the current study, we found that HSV-1 infection leads to a redistribution of speckles and paraspeckles components....

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PMID: 34675360
DOI: 10.1038/s42003-021-02742-6

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