Article
A comparative study of various methods for detection of IL28B rs12979860 in chronic hepatitis C.
Scandinavian journal of clinical and laboratory investigation - 1 Jul 2017
Monavari Seyed Hamidreza, Fateh Roohollah, Vaziri Farzam, Rahimi Jamnani Fatemeh, Anvari Enayat, Sadeghi Farzin, Afrough Parviz, Behrouzi Ava, Sakhaee Fatemeh, Meidaninikjeh Sepideh, Mollaie Hamidreza, Hadizadeh Tasbiti Alireza, Yari Shamsi, Sadeghi Maryam, Fateh Abolfazl, Siadat Seyed Davar
Abstract excerpt
Interleukin-28B (IL28B) single-nucleotide polymorphisms (SNPs) constitute important host-related factors influencing the response rate to Hepatitis C virus (HCV) standard antiviral therapy. In the last few years, several new technologies for SNP detection have been developed. However, the sensitivity and specificity of various methods are different and needs evaluation. Five different methods (resolution melting...
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