Article
High resolution melting curve assay for detecting rs12979860 IL28B polymorphisms involved in response of Iranian patients to chronic hepatitis C treatment.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Fateh Abolfazl, Aghasadeghi Mohammad Reza, Keyvani Hossein, Mollaie Hamid Reza, Yari Shamsi, Hadizade Tasbiti Ali Reza, Ghazanfari Morteza, Monavari Seyed Hamid Reza
Abstract excerpt
BACKGROUND: A recent genome-wide association study (GWAS) on patients with chronic hepatitis C (CHC) treated with peginterferon and ribavirin (pegIFN-α/RBV) identified a single nucleotide polymorphism (SNP) on chromosome 19 (rs12979860) which was strongly associated with a sustained virological response (SVR). The aim of this study was twofold: to study the relationship between IL28B rs12979860 and sustained...
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