Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in DNA Base Excision Repair Genes in Fuchs Endothelial Corneal Dystrophy.

Medical science monitor : international medical journal of experimental and clinical research - 21 Sept 2015

Wójcik Katarzyna A, Synowiec Ewelina, Polakowski Piotr, Błasiak Janusz, Szaflik Jerzy, Szaflik Jacek P

Abstract excerpt

BACKGROUND Fuchs endothelial corneal dystrophy (FECD) is a corneal disease characterized by abnormalities in the Descemet membrane and the corneal endothelium. The etiology of this disease is poorly understood. An increased level of oxidative DNA damage reported in FECD corneas suggests a role of DNA base excision repair (BER) genes in its pathogenesis. In this work, we searched for the association between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Directed DNA Polymerase
Share to DNA Glycosylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Polymerase gamma

Share to DNA Repair

Share to Fuchs' Endothelial Dystrophy

Share to Poly (ADP-Ribose) Polymerase-1

Share to Poly(ADP-ribose) Polymerases

Share to X-ray Repair Cross Complementing Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 26388025
DOI: 10.12659/MSM.894273
PMCID: PMC4582917

Genes

XRCC1
NEIL1
POLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in DNA Base Excision Repair Genes in Fuchs Endothelial Corneal Dystrophy.PMID 26388025Read ↗

Polymorphism of the flap endonuclease 1 gene in keratoconus and Fuchs endothelial corneal dystrophy.Semantic proximity Read ↗

Dysregulation of DNA repair genes in Fuchs endothelial corneal dystrophy.Semantic proximity Read ↗

Polymorphism of the DNA base excision repair genes in keratoconus.Semantic proximity Read ↗

Polymorphisms of the homologous recombination gene RAD51 in keratoconus and Fuchs endothelial corneal dystrophy.Semantic proximity Read ↗

Polymorphism of the LIG3 gene in keratoconus and Fuchs endothelial corneal dystrophy.Semantic proximity Read ↗

Polymorphism of the transferrin gene in eye diseases: keratoconus and Fuchs endothelial corneal dystrophy.Semantic proximity Read ↗

<i>TCF4</i> trinucleotide repeat expansions and UV irradiation increase susceptibility to ferroptosis in Fuchs endothelial corneal dystrophySemantic proximity Read ↗

TCF4 trinucleotide repeat expansion in Swedish cases with Fuchs' endothelial corneal dystrophy.Semantic proximity Read ↗

p53-Regulated Increase in Oxidative-Stress–Induced Apoptosis in Fuchs Endothelial Corneal Dystrophy: A Native Tissue ModelSemantic proximity Read ↗

Polymorphisms of the apoptosis-related FAS and FAS ligand genes in keratoconus and Fuchs endothelial corneal dystrophy.Semantic proximity Read ↗

TCF4 trinucleotide repeat expansions and UV irradiation increase susceptibility to ferroptosis in Fuchs endothelial corneal dystrophySemantic proximity Read ↗

The role of base excision repair in the development of primary open angle glaucoma in the Polish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.