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Article

Polymorphism of the LIG3 gene in keratoconus and Fuchs endothelial corneal dystrophy.

Cellular and molecular biology (Noisy-le-Grand, France) - 28 Mar 2015

Synowiec E, Wojcik K A, Izdebska J, Binczyk E, Szaflik J, Blasiak J, Szaflik J P

Abstract excerpt

The product of the LIG3 gene encodes DNA ligase III, which is involved in the repair of oxidatively damaged DNA in the base excision repair pathway. We hypothesized that polymorphism in this gene may change susceptibility to oxidative stress and predispose individuals to the development of kerato...

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PMID: 25817347

Genes

LIG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25817347-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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