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Article

Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma.

European journal of clinical pharmacology - 1 Dec 2015

Diekstra Meta H M, Liu Xiaoyan, Swen Jesse J, Boven Epie, Castellano Daniel, Gelderblom Hans, Mathijssen Ron H J, Rodríguez-Antona Cristina, García-Donas Jesus, Rini Brian I, Guchelaar Henk-Jan

Abstract excerpt

PURPOSE: Earlier, the association of single nucleotide polymorphisms (SNPs) with toxicity and efficacy of sunitinib has been explored in patients with metastatic renal cell carcinoma (mRCC). Recently, additional SNPs have been suggested as potential biomarkers. We investigated these novel SNPs for association with sunitinib treatment outcome in mRCC patients. METHODS: In this exploratory study, we selected SNPs...

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Identifiers

PMID: 26387812
DOI: 10.1007/s00228-015-1935-7
PMCID: PMC4643117

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POR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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