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Article

IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma.

British journal of cancer - 31 Mar 2015

Xu C-F, Johnson T, Garcia-Donas J, Choueiri T K, Sternberg C N, Davis I D, Bing N, Deen K C, Xue Z, McCann L, Esteban E, Whittaker J C, Spraggs C F, Rodríguez-Antona C, Pandite L N, Motzer R J

Abstract excerpt

BACKGROUND: We evaluated germline single nucleotide polymorphisms (SNPs) for association with overall survival (OS) in pazopanib- or sunitinib-treated patients with advanced renal cell carcinoma (aRCC). METHODS: The discovery analysis tested 27 SNPs within 13 genes from a phase III pazopanib trial (N=241, study 1). Suggestive associations were then pursued in two independent datasets: a phase III trial (COMPARZ)...

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Identifiers

PMID: 25695485
DOI: 10.1038/bjc.2015.64
PMCID: PMC4385958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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