Article
The Paracaspase MALT1.
Biochimie - 1 Mar 2016
Hachmann Janna, Salvesen Guy S
Abstract excerpt
The human paracaspase MALT1 is a caspase homolog that plays a central role in NF-κB signaling. Over the past few years it has become clear that this is due to a combination of its scaffolding and proteolytic function. Knockout mice and mice expressing a catalytically dead variant of the protease have provided valuable information. This review aims to provide an overview of recent developments regarding the...
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