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Article

Probes to monitor activity of the paracaspase MALT1.

Chemistry & biology - 22 Jan 2015

Hachmann Janna, Edgington-Mitchell Laura E, Poreba Marcin, Sanman Laura E, Drag Marcin, Bogyo Matthew, Salvesen Guy S

Abstract excerpt

The human paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) plays a central role in nuclear factor-κB (NF-κB) signaling as both a protease and scaffolding protein. Knocking out MALT1 leads to impaired NF-κB signaling and failure to mount an effective immune response. However, it is unclear to which degree it is the scaffolding function versus the proteolytic activity of MALT1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25556944
DOI: 10.1016/j.chembiol.2014.11.011
PMCID: PMC4304901

Genes

MALT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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