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Article

Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.

Annals of the rheumatic diseases - 1 Jan 2016

Yarwood Annie, Viatte Sebastien, Okada Yukinori, Plenge Robert, Yamamoto Kazuhiko, Barton Anne, Symmons Deborah, Raychaudhuri Soumya, Klareskog Lars, Gregersen Peter, Worthington Jane, Eyre Steve

Abstract excerpt

OBJECTIVES: A recent study identified 16 genetic variants associated with N-glycosylation of human IgG. Several of the genomic regions where these single nucleotide polymorphisms (SNPs) reside have also been associated with autoimmune disease (AID) susceptibility, suggesting there may be pleiotropy (genetic sharing) between loci controlling both N-glycosylation and AIDs. We investigated this by testing variants...

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Identifiers

PMID: 26386125
DOI: 10.1136/annrheumdis-2014-207210
PMCID: PMC4717396

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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