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Article

Terahertz spectroscopy of oligonucleotides in aqueous solutions.

Journal of biomedical optics - 1 Jan 2015

Tang Mingjie, Huang Qing, Wei Dongshan, Zhao Guozhong, Chang Tianying, Kou Kuan, Wang Min, Du Chunlei, Fu Wei-ling, Cui Hong-Liang

Abstract excerpt

A terahertz (THz) spectroscopic study is carried out to analyze DNA mutations in a label-free manner. Three newly designed liquid sample cells are considered and the best is selected as the sample carrier for THz transmission spectroscopic analyses. Discrimination based on spectral signatures of single-base mutations on single-stranded 20 nt oligonucleotides has been shown possible experimentally. The results...

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Identifiers

PMID: 26385423
DOI: 10.1117/1.JBO.20.9.095009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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