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Article

A resonance light scattering sensor based on methylene blue-sodium dodecyl benzene sulfonate for ultrasensitive detection of guanine base associated mutations.

Analytical and bioanalytical chemistry - 1 Oct 2012

Chen Zhanguang, Qian Sihua, Chen Junhui, Chen Xi, Zheng Liwen, Liu Jinbin

Abstract excerpt

A resonance light scattering (RLS) sensor for guanine base associated mutations has been developed on the basis of the high selectivity of methylene blue (MB) for guanine bases in the presence of sodium dodecyl benzene sulfonate (SDBS). MB, when bound to SDBS, underwent a dramatic enhancement of its RLS intensity. However, the addition of double-stranded DNA (dsDNA) and single-stranded DNA (ssDNA) caused the...

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PMID: 22885973
DOI: 10.1007/s00216-012-6289-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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