Article
Arginase 1 genetic variation is associated with the risk of vascular complications in type 2 diabetes.
Biomarkers in medicine - 1 Feb 2025
Chen X H, Li L, Ma S Y, Ling C Q, Lai J Q, Yao H J, Guo W B, Yang Y, Zhang Y, Lin W J, He F Z
Abstract excerpt
OBJECTIVE: This study aims to explore the association between arginase 1 (ARG1) genetic variation and susceptibility to type 2 diabetes (T2DM) vascular complications, a primary cause of morbidity and mortality in diabetics. METHODS: ARG1, a risk gene for cardiovascular disease, was identified from GEO datasets GSE22255 and GSE58294. The ENCODE database identified four candidate single-nucleotide polymorphism...
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