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Article

Phenotypic characterization and prognostic impact of circulating γδ and αβ T-cells in metastatic malignant melanoma.

International journal of cancer - 1 Feb 2016

Wistuba-Hamprecht Kilian, Di Benedetto Svetlana, Schilling Bastian, Sucker Antje, Schadendorf Dirk, Garbe Claus, Weide Benjamin, Pawelec Graham

Abstract excerpt

Human T cells carrying γδ T-cell receptors (TCRs) represent a minor population relative to those with αβ TCRs. There has been much interest recently in the possibility of using these γδ T-cells in cancer therapy because they can kill tumor cells in vitro in an MHC-unrestricted manner, and possess potential regulatory capability and antigen-presenting capacity. The presence of γδ T-cells in late-stage melanoma...

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Identifiers

PMID: 26383054
DOI: 10.1002/ijc.29818

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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