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Article

Differences in TCR-Vβ repertoire and effector phenotype between tumor infiltrating lymphocytes and peripheral blood lymphocytes increase with age.

PloS one - 1 Jan 2014

Shao Hongwei, Ou Yusheng, Wang Teng, Shen Han, Wu Fenglin, Zhang Wenfeng, Tao Changli, Yuan Yin, Bo Huaben, Wang Hui, Huang Shulin

Abstract excerpt

Tumor infiltrating lymphocytes (TIL) reflect the host's anti-tumor immune response, and can be a valuable predictor of prognosis. However, many properties of TIL are not fully understood. In the present study, TCR-Vβ repertoires of cancer patients were primarily analyzed by flow cytometry. Abnormally expressed TCR-Vβ subfamilies were generally found in both TIL and peripheral blood lymphocytes (PBL) of each...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Share to Receptors, Antigen, T-Cell, alpha-beta

Source

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Identifiers

PMID: 25019226
DOI: 10.1371/journal.pone.0102327
PMCID: PMC4096599

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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