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Article

Genetic variations in genes of metabolic enzymes predict postoperational prognosis of patients with colorectal cancer.

Molecular cancer - 17 Sept 2015

Dong Guanglong, He Xianli, Chen Yibing, Cao Haiyan, Wang Jiaojiao, Liu Xiaonan, Wang Shukui, Wan Shaogui, Xing Jinliang

Abstract excerpt

BACKGROUND: Genetic alterations in tricarboxylic acid (TCA) cycle metabolic enzymes were recently linked to various cancers. However, the associations of single nucleotide polymorphisms (SNPs) in genes of these enzymes have not been well studied. METHODS: We genotyped 16 SNPs from 7 genes encoding TCA cycle metabolic enzymes in 697 colorectal carcinoma (CRC) patients receiving surgical resection and analyzed...

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PMID: 26377099
DOI: 10.1186/s12943-015-0442-x
PMCID: PMC4574264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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