Article
Polymorphisms of monocarboxylate transporter genes are associated with clinical outcomes in patients with colorectal cancer.
Journal of cancer research and clinical oncology - 1 Jun 2015
Fei Fei, Guo Xu, Chen Yibing, Liu Xiaonan, Tu Jianfei, Xing Jinliang, Chen Zhinan, Ji Jiansong, He Xianli
Abstract excerpt
PURPOSE: Previous studies have demonstrated that monocarboxylate transporters (MCTs) play important roles in the development and progression of many cancers. The purpose of this study was to assess the effects of single-nucleotide polymorphisms (SNPs) of MCT genes on prognosis of colorectal cancer (CRC) patients. PATIENTS AND METHODS: Nine functional SNPs in three MCT genes (MCT1, MCT2 and MCT4) were selected and...
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