Article
Functional polymorphisms of ATP citrate lyase gene predicts clinical outcome of patients with advanced colorectal cancer.
World journal of surgical oncology - 12 Feb 2015
Xie Shuang, Zhou Feng, Wang Jiaojiao, Cao Haiyan, Chen Yibing, Liu Xiaonan, Zhang Zhaohui, Dai Jingyao, He Xianli
Abstract excerpt
BACKGROUND: Previous studies have demonstrated that ATP citrate lyase (ACLY) plays an important role in the development of many cancers. Our current study aims to assess the effects of functional single nucleotide polymorphisms (SNPs) in ACLY gene on recurrence and survival of colorectal cancer (...
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