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Article

Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients.

Medical oncology (Northwood, London, England) - 1 Nov 2014

Zhang Huiqing, Guo Xu, Dai Jingyao, Wu Yousheng, Ge Naijian, Yang Yefa, Ji Jiansong, Zhang Hongxin

Abstract excerpt

Metabolic reprogramming is an important hallmark of cancer cells, including the alterations of activity and expression in tricarboxylic acid (TCA) cycle key enzymes. Previous studies have reported the associations between tumor formation and three core enzymes involved in the TCA cycle. However, the association between functional single nucleotide polymorphisms (SNPs) in one of TCA cycle key gene isocitrate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25355558
DOI: 10.1007/s12032-014-0278-z

Genes

IDH1
IDH2
AFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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