Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and functional analysis of acute myeloid leukemia susceptibility associated single nucleotide polymorphisms at non-protein coding regions of RUNX1.

Leukemia & lymphoma - 1 Jan 2016

Xu Xin, Ren Xiuyu, Wang Haiying, Zhao Yao, Yi Zhengjun, Wang Kaifeng, Zhang Shizhuang, Wang Lin, Samuelson David J, Hu Zhenbo

Abstract excerpt

Little is known about the susceptibility to acute myeloid leukemia. We aim to search non-protein coding regions of key hematopoiesis transcription factors for genetic variations associated with acute myeloid leukemia susceptibility. We genotyped SNPs of RUNX1 P1 promoter, P2 promoter, +23 enhancer, intron 5.2 enhancer, PU.1 promoter, CEBPA promoter, and CEBPE promoter from acute myeloid leukemia patients and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Core Binding Factor Alpha 2 Subunit

Share to Gene Frequency

Share to Genetic Association Studies

Share to Leukemia, Myeloid, Acute

Share to Odds Ratio

Share to Untranslated Regions

Source

Identifiers

PMID: 26374622
DOI: 10.3109/10428194.2015.1094698

Genes

RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and functional analysis of acute myeloid leukemia susceptibility associated single nucleotide polymorphisms at non-protein coding regions of RUNX1.PMID 26374622Read ↗

Replication analysis confirms the association of several variants with acute myeloid leukemia in Chinese population.Semantic proximity Read ↗

Six novel nsSNPs affect <i>RUNX1</i> gene may leading to Acute Myeloid Leukemia (AML) using Bioinformatics approachSemantic proximity Read ↗

RUNX1 variant as a genetic predisposition factor for acute myeloid leukemia.Semantic proximity Read ↗

GATA2 rs2335052 and GATA2 rs78245253 single-nucleotide polymorphisms in Chinese patients with acute myelocytic leukemia.Semantic proximity Read ↗

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.Semantic proximity Read ↗

Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoterSemantic proximity Read ↗

Polymorphisms of the CYR61 gene in patients with acute myeloid leukemia in a Han Chinese population.Semantic proximity Read ↗

Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcriptionSemantic proximity Read ↗

Genome-Wide Association Study of Susceptibility Loci for T-Cell Acute Lymphoblastic Leukemia in Children.Semantic proximity Read ↗

Long non-coding RNA GAS5 polymorphism predicts a poor prognosis of acute myeloid leukemia in Chinese patients via affecting hematopoietic reconstitution.Semantic proximity Read ↗

A DNA Contact Map for the Mouse Runx1 Gene Identifies Novel Haematopoietic Enhancers.Semantic proximity Read ↗

Deregulated Gene Expression Profiles and Regulatory Networks in Adult and Pediatric RUNX1/RUNX1T1-Positive AML PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.