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Article

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

Oncotarget - 31 Jan 2017

Lv Hongchao, Zhang Mingming, Shang Zhenwei, Li Jin, Zhang Shanshan, Lian Duan, Zhang Ruijie

Abstract excerpt

Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, and generally considered to be caused by environment and genetic factors. In this study, we combined a genome-wide haplotype association study (GWHAS) and gene prioritization strategy to mine AML-related genetic affect factors and understand its pathogenesis. A total of 175 AML patients were downloaded from the public GEO database...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27903959
DOI: 10.18632/oncotarget.13631
PMCID: PMC5352368

Genes

FGFR2
JAK1
PDGFRA
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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