Article
Long non-coding RNA GAS5 polymorphism predicts a poor prognosis of acute myeloid leukemia in Chinese patients via affecting hematopoietic reconstitution.
Leukemia & lymphoma - 1 Aug 2017
Yan Han, Zhang Dao-Yu, Li Xi, Yuan Xiao-Qing, Yang Yong-Long, Zhu Ke-Wei, Zeng Hui, Li Xiao-Lin, Cao Shan, Zhou Hong-Hao, Zhang Wei, Chen Xiao-Ping
Abstract excerpt
Whether long non-coding RNA (lncRNA) single-nucleotide polymorphisms (SNPs) affect prognosis of acute myeloid leukemia (AML) remains unknown. To search the association between lncRNA SNPs and AML outcomes, thirty tagSNPs in five lncRNAs were genotyped in 313 AML patients. Survival analysis indicated that GAS5 rs55829688 (T > C) was significantly associated with prognosis of AML (p = 0.018). Patients with...
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