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Article

Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription

11 Jun 2012

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22689058
DOI: 10.1038/onc.2012.222

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Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcriptionPMID 22689058Read ↗

Global Identification of EVI1 Target Genes in Acute Myeloid LeukemiaSemantic proximity Read ↗

EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemiaSemantic proximity Read ↗

Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemiaSemantic proximity Read ↗

Clinical Significance of Dynamic Monitoring of EVI1 Gene Expression in Pediatric Acute Myeloid LeukemiaSemantic proximity Read ↗

EVI1 drives leukemogenesis through aberrant ERG activationSemantic proximity Read ↗

RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML.Semantic proximity Read ↗

Roles and regulations of the ETS transcription factor ELF4/MEF.Semantic proximity Read ↗

High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AMLSemantic proximity Read ↗

Repression of RUNX1 Activity by EVI1: A New Role of EVI1 in LeukemogenesisSemantic proximity Read ↗

High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities.Semantic proximity Read ↗

EVI1 exerts distinct roles in AML via ERG and cyclin D1 promoting a chemoresistant and immune-suppressive environmentSemantic proximity Read ↗

Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family.Semantic proximity Read ↗

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