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Article

RUNX1 variant as a genetic predisposition factor for acute myeloid leukemia.

Experimental and molecular pathology - 1 Aug 2020

Javadlar Masoumeh, Dastar Saba, Gharesouran Jalal, Ghafouri-Fard Soudeh, Hosseinzadeh Hassan, Moradi Mohsen, Mazraeh Shamsi Abdi, Nasiri Ganjineh Ketab Fereshteh, Rezamand Azim, Hiradfar Amirataollah, Taheri Mohammad, Rezazadeh Maryam

Abstract excerpt

Acute myeloid leukemia (AML) is the most common hematological malignancy among adults and is characterized by accumulation of immature myeloid cells. Different genetic factors have role in the occurrence of AML. Among different proteins, RUNX1 and BAALC are involved in the development AML. It has been shown that BAALC overexpression is a factor that indicate shorter disease free survival in a subset of AML...

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Share to Core Binding Factor Alpha 2 Subunit
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Leukemia, Myeloid, Acute

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Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 32294461
DOI: 10.1016/j.yexmp.2020.104440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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