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Article

Variant of the clock circadian regulator (CLOCK) gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population.

Journal of diabetes - 1 Sept 2016

Uemura Hirokazu, Katsuura-Kamano Sakurako, Yamaguchi Miwa, Arisawa Kokichi, Hamajima Nobuyuki, Hishida Asahi, Kawai Sayo, Oze Isao, Shinchi Koichi, Takashima Naoyuki, Suzuki Sadao, Nakahata Noriko, Mikami Haruo, Ohnaka Keizo, Kuriyama Nagato, Kubo Michiaki, Tanaka Hideo

Abstract excerpt

BACKGROUND: Circadian rhythm disruptions can cause various health disorders. The present study evaluated associations between single nucleotide polymorphisms in the core circadian gene clock circadian regulator (CLOCK) and the prevalence of type 2 diabetes (T2D) in the Japanese population. METHODS: Cross-sectional data were analyzed from 2485 subjects (1243 men, 1242 women; age 35-69 years) enrolled in the...

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Identifiers

PMID: 26374515
DOI: 10.1111/1753-0407.12344

Genes

CLOCK

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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