Article
MC4R rs17782313 gene polymorphism was associated with glycated hemoglobin independently of its effect on BMI in Japanese: the Shimane COHRE study.
Endocrine research - 1 Jan 2014
Mutombo Paulin Beya wa Bitadi, Yamasaki Masayuki, Hamano Tsuyoshi, Isomura Minoru, Nabika Toru, Shiwaku Kuninori
Abstract excerpt
BACKGROUND: Type 2 diabetes (T2D) is among the leading public health problems in Japan, and glycated hemoglobin (HbA1c) can be used to screen the population for T2D. Gene polymorphisms, known to be associated with obesity, may predispose individuals to T2D. Rs17782313 the melanocortin 4 receptor (MC4R) has shown one of the strongest associations with body mass index (BMI). We conducted a study to investigate...
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