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Variants in clock genes could be associated with lower risk of type 2 diabetes in an elderly Greek population.

Maturitas - 1 Oct 2021

Tsekmekidou Xanthippi, Tsetsos Fotis, Koufakis Theocharis, Georgitsi Marianthi, Papanas Nikolaos, Papazoglou Dimitrios, Roumeliotis Athanasios, Panagoutsos Stylianos, Thodis Elias, Theodoridis Marios, Passadakis Ploumis, Maltezos Efstratios, Paschou Peristera, Kotsa Kalliopi

Abstract excerpt

OBJECTIVES: Recent evidence has linked circadian rhythm dysregulation to an increased risk of metabolic disorders. This study explores a potential association between variation in genes regulating the endogenous circadian timing system (clock genes) and the risk of type 2 diabetes (T2D) in a sample of Greek elderly people. STUDY DESIGN: Variants within and upstream or downstream of PPARA, PPARD, CLOCK/TMEM165,...

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PMID: 34674804
DOI: 10.1016/j.maturitas.2021.07.004

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