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Genetic variation in the NOC gene is associated with body mass index in Chinese subjects.

PloS one - 1 Jan 2013

Chang Yi-Cheng, Chiu Yen-Feng, Liu Pi-Hua, Hee Siow Wei, Chang Tien-Jyun, Jiang Yi-Der, Lee Wei-Jei, Lee Po-Chu, Kao Hui-Yi, Hwang Juey-Jen, Chuang Lee-Ming

Abstract excerpt

UNLABELLED: Circadian clock genes are critical regulators of energy homeostasis and metabolism. However, whether variation in the circadian genes is associated with metabolic phenotypes in humans remains to be explored. In this study, we systemically genotyped 20 tag single nucleotide polymorphisms (SNPs) in 8 candidate genes involved in circadian clock, including CLOCK, BMAL1(ARNTL), PER1, PER2, CRY1, CRY2,...

Topics

Adipose Tissue
Alleles
Asian People
Blood Glucose
Blood Pressure
Body Mass Index
Casein Kinase II
Female
Genetic Association Studies
Genetic Loci
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

Male

Metabolism

Middle Aged

Nuclear Proteins

Obesity

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 23922759
DOI: 10.1371/journal.pone.0069622
PMCID: PMC3724939

Genes

BMAL1
CLOCK
CRY1
CRY2
PER1
PER2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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