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Article

Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits.

Diabetes care - 1 Aug 2015

Dashti Hassan S, Follis Jack L, Smith Caren E, Tanaka Toshiko, Garaulet Marta, Gottlieb Daniel J, Hruby Adela, Jacques Paul F, Kiefte-de Jong Jessica C, Lamon-Fava Stefania, Scheer Frank A J L, Bartz Traci M, Kovanen Leena, Wojczynski Mary K, Frazier-Wood Alexis C, Ahluwalia Tarunveer S, Perälä Mia-Maria, Jonsson Anna, Muka Taulant, Kalafati Ioanna P, Mikkilä Vera, Ordovás José M

Abstract excerpt

OBJECTIVE: Common circadian-related gene variants associate with increased risk for metabolic alterations including type 2 diabetes. However, little is known about whether diet and sleep could modify associations between circadian-related variants (CLOCK-rs1801260, CRY2-rs11605924, MTNR1B-rs1387153, MTNR1B-rs10830963, NR1D1-rs2314339) and cardiometabolic traits (fasting glucose [FG], HOMA-insulin resistance, BMI,...

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Source

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Identifiers

PMID: 26084345
DOI: 10.2337/dc14-2709
PMCID: PMC4512139

Genes

CRY2
CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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