Article
CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation.
Genome biology - 15 Sept 2015
Wang Liuyang, Oehlers Stefan H, Espenschied Scott T, Rawls John F, Tobin David M, Ko Dennis C
Abstract excerpt
Meta-analyses of genome-wide association studies (GWAS) have demonstrated that the same genetic variants can be associated with multiple diseases and other complex traits. We present software called CPAG (Cross-Phenotype Analysis of GWAS) to look for similarities between 700 traits, build trees with informative clusters, and highlight underlying pathways. Clusters are consistent with pre-defined groups and...
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