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Article

The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2016

Helsten Teresa, Elkin Sheryl, Arthur Elisa, Tomson Brett N, Carter Jennifer, Kurzrock Razelle

Abstract excerpt

PURPOSE: Molecular profiling may have prognostic and predictive value, and is increasingly used in the clinical setting. There are more than a dozen fibroblast growth factor receptor (FGFR) inhibitors in development. Optimal therapeutic application of FGFR inhibitors requires knowledge of the rates and types of FGFR aberrations in a variety of cancer types. EXPERIMENTAL DESIGN: We analyzed frequencies of FGFR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Fibroblast Growth Factor

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Source

Identifiers

PMID: 26373574
DOI: 10.1158/1078-0432.CCR-14-3212

Genes

FGFR1
FGFR2
FGFR3
FGFR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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