Article

Real-world genomic landscape of FGFR2 amplifications and fusions in solid tumors: analysis of 4,953 patients using clinical-grade NGS

2026-08-14

Abstract excerpt

Fibroblast growth factor receptor 2 (FGFR2) alterations, including amplifications and fusions, are actionable oncogenic drivers in multiple cancers, but their prevalence and genomic features are not well defined. Between October 2019 and October 2024 at Samsung Medical Center, 4,953 patients with solid tumors underwent next-generation sequencing using TruSight Oncology 500 (TSO 500) assays as part of routine clini...

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Literature Corpus work: 7efea590-bab5-5125-9a40-a6973781307f
DOI: 10.1186/s12885-026-16708-6

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